Computational Chemist / Structure-Based Drug Design

Location Wroclaw, Poland
Offer description

Job context:

The ideal candidate should possess proven scientific skills and accomplishments in the industrial setting. Primary responsibilities include Structure-Based Drug Design (SBDD), support of hit expansion, hit-to-lead, lead optimization, and molecular docking. Proficiency in drug discovery packages, e.g., Schrodinger, OpenEye, MOE, or Cresset, is a must.

Duties

Key responsibilities:

·       Structure- and ligand-based Drug Design

·       Performing protein: small molecule and protein: protein docking

·       Virtual screening of molecular databases

·       Support of hit-to-lead campaigns and integration of the biological data

·       Lead optimization for further ligand refinement

Required skills

Requirements:

·       Ph.D. in relevant discipline with a minimum of 2 years of experience in the industry

·       Expertise in molecular modeling techniques and protein docking methods, including induced fit docking

·       Good knowledge of molecular or structural biology and biophysics

·       Experience in the application of statistical methods to evaluate properties of studied biological systems

·       Computational-aided drug design skills

·       Good communication skills and aptitude for teamwork and collaboration with experimentalists

·       Attention to detail and critical thinking capabilities, excellent planning, execution, and organizational skills

Description

We offer:

·       Full-time employment in a quickly growing biotechnological enterprise

·       Private healthcare plan

·       Subsidy to sports activity package

·       External and internal training in hard and soft skills, as well as participation in conferences

Last modified Thursday, December 22, 2022